Шварц Педиатрический СКФ, полная модель (2009)

Для полного расчета педиатрической СКФ по методу Шварца требуется рост, сывороточный креатинин, цистатин С, азот мочевины крови и пол.

The original Schwartz eGFR formula was devised in the mid-1970s to estimate GFR in children. This model was felt to overestimates GFR, likely a result of a change in methods used to measure creatinine.

In 2009, Schwartz et al developed a revised estimated GFR formula using data from cohort of children in the Chronic Kidney Disease in Children (CKiD) study.

This model is appropriate for children between the ages of 1 to 16 yr.

The linear regression analyses generated a model that included the following:

• height (meters)
• serum creatinine (mg/dL)
• cystatin C (mg/L)
• Blood urea nitrogen (mg/dL)
• Gender

The full equation is as follows:

• GFR (ml/min per 1.73 m2) =
• 39.1[height/creatinine]^0.516 X [1.8/cystatin C]^0.294 [30/BUN]^0.169 [1.099]^male [height/1.4]^0.188

Given the complexity of this formula, a "bedside" version requiring only height and creatinine was developed:

eGFR = 0.413 X (height/serum creatinine),
where height is in cm, and creatinine is in mg/dL